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Vid upprepad dosering till den ammande kvinnan kan petidin och metaboliten (norpetidin) medföra CNS-påverkan hos barnet. Amning vid upprepad dosering skall endast ske efter särskilt övervägande.
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Contraindicated. Nirmatrelvir/ritonavir is contraindicated with drugs that are really depending on CYP3A for clearance and for which elevated concentrations are connected with critical and/or life-threatening reactions.
within just fourteen days of having MAO inhibitors; if linezolid or IV methylene blue (MAOIs) need to be administered, discontinue serotonergic drug immediately and keep track of for CNS toxicity; may perhaps resume 24 hr following very last linezolid or methylene blue dose, or soon after two months of checking, whichever will come initially
Opioid agonists Additive results on CNS depression, respiratory despair and hypotension can happen with concomitant usage of opioid agonist analgesics.
gepirone and meperidine both equally improve serotonin levels. Use Caution/Monitor. keep track of for signs or symptoms of serotonin syndrome when gepirone is utilized gepirone with other medicines that could have an affect on the serotonergic neurotransmitter methods. If serotonin syndrome occurs, look at discontinue gepirone and/or concomitant serotonergic drug.
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Danish writer Tove Ditlevsen suffered a lifelong dependancy to pethidine after her partner, a physician, had injected her with Demerol to be a painkiller for an unlawful abortion in 1944.[forty eight]
Pethidine is rapidly hydrolysed from the liver to pethidinic acid and is additionally demethylated to norpethidine, that has 50 % the analgesic exercise of pethidine but a longer elimination half-daily life (8–12 hrs);[39] accumulating with standard administration, or in kidney failure. Norpethidine is toxic and has convulsant and hallucinogenic effects.
Läkemedlet är narkotikum enligt Läkemedelsverkets fileörteckning II. Kan kräva intyg för att medföras på resa inom Schengenområdet. Läs mer hos Läkemedelsverket.
Petidin Meda innehåller den aktiva substansen petidin, som petidinhydroklorid, och hör until en grupp starka smärtstillande läkemedel som kallas opioider. Petidin Meda används vid svåra smärttillstånd.
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IV injection: Inject 10 mg/mL incredibly bit by bit; opiate antagonist and facilities for administration of oxygen and control of respiration really should be out there during and instantly soon after administration